circRNA basic information
circBase ID: -
Name: hsa_circ_NRIP1
Synonym: circNRIP1
Host Gene: hsa-miR-339-5p
 
 
 
Disease basic information
DO ID:
 3021
DO name: acute kidney failure
Disease details: acute kidney injury
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: HK2 cells.
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: OXSR1
Associated microRNA: hsa-miR-339-5p
Biological function: CircNRIP1 depletion protected HK2 cells from LPS-induced apoptosis and inflammation.
Molecular mechanism: MiR-339-5p expression was downregulated in the blood of septic AKI patients, and miR-339-5p combined with circNRIP1.
Survival: -
Supported No.:
 1
Description:

CircNRIP1 depletion ameliorated LPS-induced HK2 cell damage by regulating the miR-339-5p/OXSR1 pathway.
Other information
Title:

CircNRIP1 KNOCKDOWN ALLEVIATES LIPOPOLYSACCHARIDE-INDUCED HUMAN KIDNEY 2 CELL APOPTOSIS AND INFLAMMATION THROUGH miR-339-5p/OXSR1 PATHWAY.

Journal: Shock
Published: 2023/1/8
PubMed ID: 36609531