circRNA basic information
circBase ID: -
Name: hsa_circ_TMEM181
Synonym: circTMEM181
Host Gene: hsa-miR-519a-5p
 
 
 
Disease basic information
DO ID:
 684
DO name: hepatocellular carcinoma
Disease details: hepatocellular carcinoma
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: SNU-449, HepG2, HepG2/C3A, MHCC97L, MHCC97H, HCCLM3
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DN
Associated gene: ARHGAP29
Associated microRNA: hsa-miR-519a-5p
Biological function: inhibits migration and invasion
Molecular mechanism: circTMEM181/hsa-miR-519a-5p/ARHGAP29 axis
Survival: better
Supported No.:
 2
Description:

These data provide the first evidence of clinical significance and function of circTMEM181, and suggest the circTMEM181/miR-519a-5p/ARHGAP29 axis in HCC development.
Other information
Title:

circTMEM181 upregulates ARHGAP29 to inhibit hepatocellular carcinoma migration and invasion by sponging miR-519a-5p.

Journal: Hepatol Res
Published: 2022/12/16
PubMed ID: 36519254