circRNA basic information
circBase ID: hsa_circ_0046701
Name: hsa_circ_YES1
Synonym: -
Host Gene: hsa-miR-142-3p
 
 
 
Disease basic information
DO ID:
 0060108
DO name: brain glioma
Disease details: glioma
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: normal human astrocytes (NHAs), glioma cell lines (U251, U373, SHG44)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: ITGB8
Associated microRNA: hsa-miR-142-3p
Biological function: promotes cell proliferation and invasion
Molecular mechanism: increasing the expression of hsa-miR-142-3p target ITGB8
Survival: -
Supported No.:
 1
Description:

The results demonstrated that the hsa_circ_0046701/miR-142-3p/ITGB8 axis might play critical regulatory roles in the pathogenesis and development of glioma.
Other information
Title:

A novel circular RNA, hsa_circ_0046701, promotes carcinogenesis by increasing the expression of miR-142-3p target ITGB8 in glioma.

Journal: Biochem Biophys Res Commun
Published: 2018/1/18
PubMed ID: 29337055