circRNA basic information
circBase ID: -
Name: hsa_circ_RNF10
Synonym: circRNF10
Host Gene: hsa-miR-934
 
 
 
Disease basic information
DO ID:
 1612
DO name: breast cancer
Disease details: breast cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: BT-549, MDA-MB-231
circRNA-disease information
Detected method:
Q
M
Detected method confidence High
Expression pattern:
DN
Associated gene: PTEN
Associated microRNA: hsa-miR-934
Biological function: circRNF10 Suppresses BC Cell Proliferation, Invasion, and Migration and Enhances the Killing Efficiency of NK-92MI Cells
Molecular mechanism: PI3k-Akt pathway, miRNA sponge
Survival: better
Supported No.:
 3
Description:

These findings reveal that circRNF10 functions as a novel anti-oncogene in BC via sponging miR-934 and suppressing the PI3K/Akt/MICA pathway.
Other information
Title:

circRNF10 Regulates Tumorigenic Properties and Natural Killer Cell-Mediated Cytotoxicity against Breast Cancer through the miR-934/PTEN/PI3k-Akt Axis.

Journal: Cancers (Basel)
Published: 2022/12/12
PubMed ID: 36497344