circRNA basic information
circBase ID: -
Name: hsa_circ_NFIX
Synonym: CircNFIX
Host Gene: -
 
 
 
Disease basic information
DO ID:
 2394
DO name: ovarian cancer
Disease details: ovarian cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: 3AO, OVCAR3, A2780, SKOV3
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: -
Biological function: proliferation, invasion, and stemness
Molecular mechanism: -
Survival: -
Supported No.:
 2
Description:

CircNFIX improved the mRNA stability and translation of SH3RF3 via recruiting LIN28B, thus promoting the proliferation, invasion, and stemness properties of OC cells in vitro.
Other information
Title:

CircNFIX stimulates the proliferation, invasion, and stemness properties of ovarian cancer cells by enhancing SH3RF3 mRNA stability via binding LIN28B.

Journal: Kaohsiung J Med Sci
Published: 2022/12/11
PubMed ID: 36495291