circRNA basic information
circBase ID: -
Name: hsa_circ_LPAR3
Synonym: CircLPAR3
Host Gene: hsa-miR-873-5p
 
 
 
Disease basic information
DO ID:
 3748
DO name: esophagus squamous cell carcinoma
Disease details: esophageal squamous cell carcinoma
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: TE-1, ECA109, KYSE150
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: LDHA
Associated microRNA: hsa-miR-873-5p
Biological function: cell growth, metastasis, and Warburg effect
Molecular mechanism: miRNA sponge
Survival: -
Supported No.:
 2
Description:

CircLPAR3 knockdown suppressed ESCC cell growth, metastasis, and Warburg effect by miR-873-5p/LDHA axis, implying a promising molecular target for ESCC therapy.
Other information
Title:

CircLPAR3 knockdown suppresses esophageal squamous cell carcinoma cell oncogenic phenotypes and Warburg effect through miR-873-5p/LDHA axis.

Journal: Hum Exp Toxicol
Published: 2022/12/10
PubMed ID: 36484173