circRNA basic information
circBase ID: -
Name: mmu_circ_Atp9b
Synonym: -
Host Gene: mmu-miR-138-5p
 
 
 
Disease basic information
DO ID:
 8398
DO name: osteoarthritis
Disease details: osteoarthritis
Species: mouse
Species details: mouse
Sample type: tissue
Sample type details: -
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: mmu-miR-138-5p
Biological function: -
Molecular mechanism: circRNA_Atp9b regulates OA progression by modulating ECM catabolism and inflammation in chondrocytes via sponging mmu-miR-138-5p
Survival: -
Supported No.:
 1
Description:

Taken together, these results suggest that circRNA_Atp9b regulates OA progression by modulating ECM catabolism and inflammation in chondrocytes via sponging miR-138-5p. Our findings provide novel insight into the regulatory mechanism of circRNA_Atp9b in OA and may contribute to establishing potential therapeutic strategies.
Other information
Title:

Circular RNA Atp9b, a competing endogenous RNA, regulates the progression of osteoarthritis by targeting miR-138-5p.

Journal: Gene
Published: 2018/1/7
PubMed ID: 29305974