circRNA basic information
circBase ID: -
Name: hsa_circ_PTPRF
Synonym: circPTPRF
Host Gene: hsa-miR-1208
 
 
 
Disease basic information
DO ID:
 3073
DO name: brain glioblastoma multiforme
Disease details: glioblastoma
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: U87, LN229, glioma stem cells (GSCs)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: YY1
Associated microRNA: hsa-miR-1208
Biological function: proliferation, invasion and neurosphere formation
Molecular mechanism: miRNA sponge
Survival: poor
Supported No.:
 1
Description:

circPTPRF was a miR-1208 sponge for upregulating YY1 expression to promote proliferation, invasion and neurosphere formation abilities of GBM in vitro. In conclusion, the circPTPRF/miR-1208/YY1 axis can regulate GBM progression.
Other information
Title:

Circular RNA circPTPRF promotes the progression of GBM via sponging miR-1208 to up-regulate YY1.

Journal: Cancer Cell Int
Published: 2022/11/19
PubMed ID: 36397164