circRNA basic information
circBase ID: -
Name: hsa_circ_MBNL3
Synonym: Circ_MBNL3
Host Gene: hsa-miR-873-5p
 
 
 
Disease basic information
DO ID:
 684
DO name: hepatocellular carcinoma
Disease details: hepatocellular carcinoma
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: human HCC cell lines (Hep3B, Huh1), a normal adult liver epithelial (THLE-2)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DN
Associated gene: PHF2
Associated microRNA: hsa-miR-873-5p
Biological function: proliferation, migration, and invasion and apoptosis
Molecular mechanism: miRNA sponge
Survival: -
Supported No.:
 2
Description:

Circ_MBNL3 restrained the proliferation, migration, and invasion and promoted the apoptosis of HCC cells depending on the regulation of miR-873-5p/PHF2 axi.
Other information
Title:

Circ_MBNL3 Restrains Hepatocellular Carcinoma Progression by Sponging miR-873-5p to Release PHF2.

Journal: Biochem Genet
Published: 2022/11/16
PubMed ID: 36380035