circRNA basic information
circBase ID: -
Name: hsa_circ_FOXO3
Synonym: Circ_FOXO3
Host Gene: hsa-miR-122-5p
 
 
 
Disease basic information
DO ID:
 10941
DO name: intracranial aneurysm
Disease details: intracranial aneurysms
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: HBVSMC
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: KLF6
Associated microRNA: hsa-miR-122-5p
Biological function: proliferation
Molecular mechanism: miRNA sponge
Survival: -
Supported No.:
 1
Description:

circ_FOXO3 suppresses H2O2-induced proliferation of HBVSMC but promotes apoptosis via modulation of miR-122-5p/KLF6 axis.
Other information
Title:

Circ_FOXO3 regulates KLF6 through sponge adsorption of miR-122-5p to repress H2O2-induced HBVSMC proliferation, thus promoting IA development in vitro model.

Journal: Acta Biochim Pol
Published: 2022/10/23
PubMed ID: 36272155