circRNA basic information
circBase ID: -
Name: hsa_circ_UBXN7
Synonym: CircUBXN7
Host Gene: hsa-miR-622
 
 
 
Disease basic information
DO ID:
 11394
DO name: adult respiratory distress syndrome
Disease details: acute respiratory distress syndrome
Species: human
Species details: human
Sample type: cell line
Sample type details: A549, Beas-2B
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: IL6ST
Associated microRNA: hsa-miR-622
Biological function: cell proliferation and cell apoptosis
Molecular mechanism: miRNA sponge
Survival: -
Supported No.:
 1
Description:

circUBXN7 suppressed cell proliferation and facilitated cell apoptosis by sponging miR-622 and regulating IL6ST, to activate the JAK1/STAT3 signaling pathway in LPS-induced A549 and Beas-2B cell injury.
Other information
Title:

CircUBXN7 suppresses cell proliferation and facilitates cell apoptosis in lipopolysaccharide-induced cell injury by sponging miR-622 and regulating the IL6ST/JAK1/STAT3 axis.

Journal: Int J Biochem Cell Biol
Published: 2022/10/19
PubMed ID: 36257578