circRNA basic information
circBase ID: -
Name: hsa_circ_MAT2B
Synonym: CircMAT2B
Host Gene: hsa-miR-491-5p
 
 
 
Disease basic information
DO ID:
 5520
DO name: head and neck squamous cell carcinoma
Disease details: head and neck squamous cell carcinoma
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: human HNSCC cell lines (CAL27, Fadu, HN-30, HN-6, SCC-9, SCC-25)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: ASCT2
Associated microRNA: hsa-miR-491-5p
Biological function: cell proliferation, migration, invasion, and glutaminolysis
Molecular mechanism: miRNA sponge
Survival: poor
Supported No.:
 1
Description:

circMAT2B could modulate the processes of cell proliferation, migration, invasion, and glutaminolysis of HNSCC cells partly via the miR-491-5p/ASCT2 axis.
Other information
Title:

CircMAT2B facilitates the progression of head and neck squamous cell carcinoma via sponging miR-491-5p to trigger ASCT2-mediated glutaminolysis.

Journal: Mol Cell Biochem
Published: 2022/10/12
PubMed ID: 36219356