circRNA basic information
circBase ID: -
Name: rno_circ_Nf1
Synonym: CircNf1
Host Gene: -
 
 
 
Disease basic information
DO ID:
2560
DO name: morphine dependence
Disease details: morphine analgesic tolerance
Species: rat
Species details: rat
Sample type: tissue
Sample type details: -
circRNA-disease information
Detected method:
S
Detected method confidence Low
Expression pattern:
DS
Associated gene: -
Associated microRNA: -
Biological function: -
Molecular mechanism: -
Survival: -
Supported No.:
1
Description:

circNf1 functions as a sponge for miR-330-3p and miR-665 and induces the upregulation of CXCL12 at both transcriptional and translational levels in morphine-treated rats.

Other information
Title:

CircNf1-mediated CXCL12 expression in the spinal cord contributes to morphine analgesic tolerance.

Journal: Brain Behav Immun
Published: 2022/10/7
PubMed ID: 36202171