circRNA basic information
circBase ID: -
Name: hsa_circ_TADA2A
Synonym: CircTADA2A
Host Gene: hsa-miR-214-3p
 
 
 
Disease basic information
DO ID:
 3908
DO name: lung non-small cell carcinoma
Disease details: non-small cell lung cancer
Species: human
Species details: human
Sample type: cell line
Sample type details: human lung epithelial cell line (BEAS-2B), human NSCLC cell lines (A549, NCI-H1299, PC9)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: MAPK8
Associated microRNA: hsa-miR-214-3p
Biological function: invasion and migration
Molecular mechanism: miRNA sponge
Survival: -
Supported No.:
 6
Description:

CircTADA2A enhances MAPK8 expression by serving as a miR-214-3p sponge and EIF4A3 decoy, consequently promoting invasion and migration of NSCLC cells.
Other information
Title:

CircTADA2A up-regulates MAPK8 by targeting MiR-214-3p and recruiting EIF4A3 to promote the invasion and migration of non-small cell lung cancer cells.

Journal: Histol Histopathol
Published: 2022/10/5
PubMed ID: 36193940