circRNA basic information
circBase ID: hsa_circ_0005050
Name: -
Synonym: Circ_0005050
Host Gene: -
 
 
 
Disease basic information
DO ID:
 50866
DO name: oral squamous cell carcinoma
Disease details: oral squamous cell carcinoma
Species: human
Species details: human
Sample type: cell line
Sample type details: HOEC
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: -
Biological function: cell proliferation and cell apoptosis
Molecular mechanism: JAK/STAT3 signaling pathway
Survival: -
Supported No.:
 2
Description:

circ_0005050 regulates miR-23a-3p/miR-625-5p/STAT3 axis to activate JAK/STAT3 signaling pathway, consequently facilitating OSCC cell proliferation and inhibiting cell apoptosis.
Other information
Title:

Circ_0005050 promotes the proliferation of oral squamous cell carcinoma and inhibits the apoptosis by activating JAK/STAT3 signaling pathway.

Journal: Pathol Res Pract
Published: 2022/9/27
PubMed ID: 36155326