circRNA basic information
circBase ID: hsa_circ_0000479
Name: -
Synonym: -
Host Gene: hsa-miR-149-5p
 
 
 
Disease basic information
DO ID:
 0080600
DO name: COVID-19
Disease details: COVID-19
Species: human
Species details: human
Sample type: cell line
Sample type details: peripheral blood mononuclear cells
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: RIG-I, IL-6
Associated microRNA: hsa-miR-149-5p
Biological function: -
Molecular mechanism: -
Survival: -
Supported No.:
 1
Description:

Upregulation of hsa_circ_0000479, RIG-I, and IL-6, and downregulation of hsa-miR-149-5p, along with correlation studies, indicate that hsa_circ_0000479/hsa-miR-149-5p/RIG-I, IL-6 axis could play a role in regulating the immune response against SARS-CoV-2. However, more studies are needed in this area.
Other information
Title:

Hsa_circ_0000479/Hsa-miR-149-5p/RIG-I, IL-6 Axis: A Potential Novel Pathway to Regulate Immune Response against COVID-19.

Journal: Can J Infect Dis Med Microbiol
Published: 2022/9/10
PubMed ID: 36081604