circRNA basic information
circBase ID: -
Name: hsa_circ_TYMP1
Synonym: Circ TYMP1
Host Gene: hsa-miR-182A-3p
 
 
 
Disease basic information
DO ID:
 2394
DO name: ovarian cancer
Disease details: ovarian cancer
Species: human
Species details: human
Sample type: cell line
Sample type details: A2780, SKOV3, ES2
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: TGF1B
Associated microRNA: hsa-miR-182A-3p
Biological function: cisplatin resistance
Molecular mechanism: miRNA sponge
Survival: -
Supported No.:
 1
Description:

TYMP1 sequesters miR-182A-3p and promotes TGF1B in ovarian carcinoma, boosting carcinogenesis and cisplatin resistance.
Other information
Title:

Circ TYMP1 Inhibits Carcinogenesis and Cisplatin Resistance in Ovarian Cancer by Reducing Smad2/3 Phosphorylation via a MicroRNA-182A-3p/TGF1B Axis.

Journal: Contrast Media Mol Imaging
Published: 2022/9/9
PubMed ID: 36072623