circRNA basic information
circBase ID: -
Name: hsa_circ_PDK1
Synonym: circPDK1
Host Gene: hsa-miR-628-3p
 
 
 
Disease basic information
DO ID:
 1793
DO name: pancreatic cancer
Disease details: pancreatic cancer
Species: human
Species details: human
Sample type: tissue
Sample type details: -
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: BPTF
Associated microRNA: hsa-miR-628-3p
Biological function: -
Molecular mechanism: miRNA sponge
Survival: poor
Supported No.:
 1
Description:

circPDK1 was activated by HIF1A at the transcriptional level by modulating the miR-628-3p/BPTF axis and degrading BIN1.
Other information
Title:

Hypoxia-induced exosomal circPDK1 promotes pancreatic cancer glycolysis via c-myc activation by modulating miR-628-3p/BPTF axis and degrading BIN1.

Journal: J Hematol Oncol
Published: 2022/9/7
PubMed ID: 36068586