circRNA basic information
circBase ID: -
Name: hsa_circ_CRKL
Synonym: circCRKL
Host Gene: hsa-miR-877-5p
 
 
 
Disease basic information
DO ID:
 8552
DO name: chronic myeloid leukemia
Disease details: chronic myeloid leukemia
Species: human
Species details: human
Sample type: cell line
Sample type details: BCR-ABL(+)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: BCR-ABL
Associated microRNA: hsa-miR-877-5p
Biological function: -
Molecular mechanism: miRNA sponge
Survival: -
Supported No.:
 1
Description:

circCRKL is specifically expressed and regulates BCR-ABL expression level via decoying miR-877-5p in BCR-ABL(+) cells.
Other information
Title:

circCRKL, a circRNA derived from CRKL, regulates BCR-ABL via sponging miR-877-5p to promote chronic myeloid leukemia cell proliferation.

Journal: J Transl Med
Published: 2022/9/5
PubMed ID: 36058922