circRNA basic information
circBase ID: hsa_circ_0027446
Name: -
Synonym: Circ_0027446
Host Gene: hsa-miR-129-5p
 
 
 
Disease basic information
DO ID:
 1781
DO name: thyroid gland cancer
Disease details: thyroid cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: FTC-133, 8505_, IHH-4, TPC-1
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: CLDN1
Associated microRNA: hsa-miR-129-5p
Biological function: -
Molecular mechanism: miRNA sponge
Survival: -
Supported No.:
 1
Description:

Circ_0027446 contributed to PTC cell tumor properties by regulating the miR-129-5p/CLDN1 pathway, showing circ_0027446 might be a therapeutic target in PTC.
Other information
Title:

Circ_0027446 induces CLDN1 expression to promote papillary thyroid cancer cell malignancy by binding to miR-129-5p.

Journal: Pathol Res Pract
Published: 2022/9/5
PubMed ID: 36058014