circRNA basic information
circBase ID: -
Name: hsa_circ_SMARCC1
Synonym: CircSMARCC1
Host Gene: hsa-miR-1322
 
 
 
Disease basic information
DO ID:
 10283
DO name: prostate cancer
Disease details: prostate cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: PC-3, DU145, 22Rv1, C4_2, LNCaP
circRNA-disease information
Detected method:
Q
S
Detected method confidence High
Expression pattern:
UP
Associated gene: CCL20/CCR6
Associated microRNA: hsa-miR-1322
Biological function: -
Molecular mechanism: miRNA sponge
Survival: -
Supported No.:
 1
Description:

CircSMARCC1 up-regulates the chemokine CCL20 secretion by sponging miR-1322, which is involved in the crosstalk between tumor cells and TAMs by targeting CCL20/CCR6 signaling to promote progression of PCa.
Other information
Title:

CircSMARCC1 facilitates tumor progression by disrupting the crosstalk between prostate cancer cells and tumor-associated macrophages via miR-1322/CCL20/CCR6 signaling.

Journal: Mol Cancer
Published: 2022/9/1
PubMed ID: 36045408