circRNA basic information
circBase ID: -
Name: rno_circ_SMOC1
Synonym: CircSMOC1
Host Gene: rno-miR-329-3p
 
 
 
Disease basic information
DO ID:
 14557
DO name: primary pulmonary hypertension
Disease details: pulmonary arterial hypertension
Species: rat
Species details: rat
Sample type: tissue
Sample type details: -
circRNA-disease information
Detected method:
Q
S
Detected method confidence High
Expression pattern:
DN
Associated gene: -
Associated microRNA: rno-miR-329-3p
Biological function: metabolic reprogramming
Molecular mechanism: miRNA sponge
Survival: -
Supported No.:
 1
Description:

circSMOC1 is crucially involved in the metabolic reprogramming of pulmonary artery smooth muscle cells through PTBP1 and miR-329-3p to regulate pulmonary vascular remodeling in pulmonary arterial hypertension.
Other information
Title:

Reduced CircSMOC1 Level Promotes Metabolic Reprogramming via PTBP1 (Polypyrimidine Tract-Binding Protein) and miR-329-3p in Pulmonary Arterial Hypertension Rats.

Journal: Hypertension
Published: 2022/8/24
PubMed ID: 35997022