circRNA basic information
circBase ID: -
Name: hsa_circ_MELK
Synonym: circMELK
Host Gene: hsa-miR-497-5p
 
 
 
Disease basic information
DO ID:
 8398
DO name: osteoarthritis
Disease details: osteoarthritis
Species: human
Species details: human
Sample type: tissue
Sample type details: -
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: MYD88
Associated microRNA: hsa-miR-497-5p
Biological function: apoptosis and autophagy
Molecular mechanism: miRNA sponge
Survival: -
Supported No.:
 1
Description:

CircMELK promotes chondrocyte apoptosis and inhibits autophagy in OA by regulating MYD88/NF-kappaB signaling axis through miR-497-5p.
Other information
Title:

Circular RNA MELK Promotes Chondrocyte Apoptosis and Inhibits Autophagy in Osteoarthritis by Regulating MYD88/NF-kappaB Signaling Axis through MicroRNA-497-5p.

Journal: Contrast Media Mol Imaging
Published: 2022/8/23
PubMed ID: 35992546