circRNA basic information
circBase ID: -
Name: mmu_circ_SV2b
Synonym: CircSV2b
Host Gene: mmu-miR-5107-5p
 
 
 
Disease basic information
DO ID:
 14330
DO name: Parkinson disease
Disease details: Parkinson disease
Species: mouse
Species details: mouse
Sample type: PDX
Sample type details: -
circRNA-disease information
Detected method:
Q
S
Detected method confidence High
Expression pattern:
UP
Associated gene: Foxk1
Associated microRNA: mmu-miR-5107-5p
Biological function: -
Molecular mechanism: miRNA sponge
Survival: -
Supported No.:
 1
Description:

the miR-5107-5p-Foxk1-Akt1 axis might serve as a key target of circSV2b overexpression in PD treatment, and highlighted the significant change of circSV2b in serum exosomes.
Other information
Title:

CircSV2b participates in oxidative stress regulation through miR-5107-5p-Foxk1-Akt1 axis in Parkinson disease.

Journal: Redox Biol
Published: 2022/8/17
PubMed ID: 35973363