circRNA basic information
circBase ID: hsa_circ_0002194
Name: -
Synonym: circ_0002194
Host Gene: hsa-miR-637
 
 
 
Disease basic information
DO ID:
 1936
DO name: atherosclerosis
Disease details: atherosclerosis
Species: human
Species details: human
Sample type: cell line
Sample type details: HUVECs
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DN
Associated gene: PACS2
Associated microRNA: hsa-miR-637
Biological function: -
Molecular mechanism: miRNA sponge
Survival: -
Supported No.:
 1
Description:

circ_0002194 facilitated endothelial cell dysfunction in atherosclerosis partly through upregulating PACS2 by targeting miR-637.
Other information
Title:

Knockdown of circ_0002194 protects against oxidized low-density lipoprotein-induced cell damage via the regulation of the miR-637/PACS2 axis in human vascular endothelial cells.

Journal: Interact Cardiovasc Thorac Surg
Published: 2022/8/12
PubMed ID: 35951762