circRNA basic information
circBase ID: -
Name: hsa_circ_NFKB1
Synonym: circNFKB1
Host Gene: -
 
 
 
Disease basic information
DO ID:
 8398
DO name: osteoarthritis
Disease details: osteoarthritis
Species: human
Species details: human
Sample type: cell line
Sample type details: -
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DS
Associated gene: -
Associated microRNA: -
Biological function: -
Molecular mechanism: -
Survival: -
Supported No.:
 2
Description:

circNFKB1 interacted with alpha-enolase (ENO1), regulated the expression of its parental gene NFKB1 and sustained the activation of NF-kappaB signaling pathway in chondrocytes.
Other information
Title:

Circular RNA circNFKB1 promotes osteoarthritis progression through interacting with ENO1 and sustaining NF-kappaB signaling.

Journal: Cell Death Dis
Published: 2022/8/10
PubMed ID: 35945200