circRNA basic information
circBase ID: -
Name: hsa_circ_COL1A2
Synonym: circCOL1A2
Host Gene: hsa-miR-646
 
 
 
Disease basic information
DO ID:
 8947
DO name: diabetic retinopathy
Disease details: diabetic retinopathy
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: RMECs
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: FGF7
Associated microRNA: hsa-miR-646
Biological function: migration, proliferation, angiogenesis
Molecular mechanism: miRNA sponge
Survival: -
Supported No.:
 4
Description:

CircCOL1A2 silencing can suppress HG-induced migration, proliferation, angiogenesis, BRB injury and inflammation in RMECs through miR-646/FGF7 axis.
Other information
Title:

Down-Regulation of circCOL1A2 Suppresses the Dysfunction of Diabetes-Related Retinal Microvascular Endothelial Cells via miR-646/FGF7 Axis.

Journal: Curr Eye Res
Published: 2022/8/5
PubMed ID: 35924466