circRNA basic information
circBase ID: -
Name: hsa_circ_RPPH1
Synonym: circRPPH1
Host Gene: -
 
 
 
Disease basic information
DO ID:
 3073
DO name: brain glioblastoma multiforme
Disease details: glioblastoma multiforme
Species: human
Species details: human
Sample type: cell line
Sample type details: glioma stem cells
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: -
Biological function: self-renewal
Molecular mechanism: TGF-beta signal pathway
Survival: -
Supported No.:
 1
Description:

UPF1/circRPPH1/ATF3 maintains the potential self-renewal of GSCs through interacting with RNA-binding protein and activating the TGF-beta signal pathway.
Other information
Title:

UPF1/circRPPH1/ATF3 feedback loop promotes the malignant phenotype and stemness of GSCs.

Journal: Cell Death Dis
Published: 2022/7/24
PubMed ID: 35871061