circRNA basic information
circBase ID: -
Name: hsa_circ_LONP2
Synonym: CircLONP2
Host Gene: hsa-miR-27b-3p
 
 
 
Disease basic information
DO ID:
 3748
DO name: esophagus squamous cell carcinoma
Disease details: esophageal squamous cell carcinoma
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: ECA109, EC9706, EC-1, ESC-410, KYSE30
circRNA-disease information
Detected method:
Q
S
M
Detected method confidence High
Expression pattern:
UP
Associated gene: ZEB1
Associated microRNA: hsa-miR-27b-3p
Biological function: metastasis
Molecular mechanism: miRNA sponge
Survival: poor
Supported No.:
 1
Description:

circLONP2/miR-27b-3p/ZEB1 axis promotes ESCC metastasis via regulating epithelial-to-mesenchymal transition (EMT)-related protein.
Other information
Title:

CircLONP2 Accelerates Esophageal Squamous Cell Carcinoma Progression via Direct MiR-27b-3p-ZEB1 Axis.

Journal: Front Oncol
Published: 2022/7/23
PubMed ID: 35865464