circRNA basic information
circBase ID: hsa_circ_0000045
Name: -
Synonym: circ_0000045
Host Gene: -
 
 
 
Disease basic information
DO ID:
 5520
DO name: head and neck squamous cell carcinoma
Disease details: head and neck squamous cell carcinoma
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: FaDu, SCC-9
circRNA-disease information
Detected method:
Q
S
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: -
Biological function: cell proliferation, migration, and invasion
Molecular mechanism: -
Survival: -
Supported No.:
 1
Description:

The high expression of circ_0000045; therefore, promoted cell proliferation, migration, and invasion during HNSCCs development through regulating HSP70 protein and mitogen-activated protein kinase signaling.
Other information
Title:

circ_0000045 promotes proliferation, migration, and invasion of head and neck squamous cell carcinomas via regulating HSP70 and MAPK pathway.

Journal: BMC Cancer
Published: 2022/7/20
PubMed ID: 35854245