circRNA basic information
circBase ID: -
Name: -
Synonym: circ_001678
Host Gene: hsa-miR-326
 
 
 
Disease basic information
DO ID:
 3908
DO name: lung non-small cell carcinoma
Disease details: non-small cell lung cancer
Species: human
Species details: human
Sample type: tissue
Sample type details: -
circRNA-disease information
Detected method:
S
Detected method confidence Low
Expression pattern:
UP
Associated gene: ZEB1
Associated microRNA: hsa-miR-326
Biological function: immune escape
Molecular mechanism: miRNA sponge
Survival: -
Supported No.:
 1
Description:

circ_001678 sponges miR-326 to up-regulate ZEB1 expression and induce the PD-1/PD-L1 pathway-dependent immune escape.
Other information
Title:

Immunomodulatory functions of the circ_001678/miRNA-326/ZEB1 axis in non-small cell lung cancer via the regulation of PD-1/PD-L1 pathway.

Journal: Hum Mol Genet
Published: 2022/7/19
PubMed ID: 35848890