circRNA basic information
circBase ID: -
Name: hsa_circ_WDR62
Synonym: circWDR62
Host Gene: hsa-miR-370-3p
 
 
 
Disease basic information
DO ID:
 0060108
DO name: brain glioma
Disease details: glioma
Species: human
Species details: human
Sample type: cell line
Sample type details: U343, U251
circRNA-disease information
Detected method:
Q
M
Detected method confidence High
Expression pattern:
UP
Associated gene: MGMT
Associated microRNA: hsa-miR-370-3p
Biological function: TMZ resistance
Molecular mechanism: miRNA sponge
Survival: poor
Supported No.:
 1
Description:

exosome-mediated delivery of circWDR62 can promote TMZ resistance and malignant progression via targeting of the miR-370-3p/MGMT axis in vitro and in vivo in glioma.
Other information
Title:

Exosomal circWDR62 promotes temozolomide resistance and malignant progression through regulation of the miR-370-3p/MGMT axis in glioma.

Journal: Cell Death Dis
Published: 2022/7/12
PubMed ID: 35817771