circRNA basic information
circBase ID: hsa_circ_0012673
Name: hsa_circ_DHCR24
Synonym: -
Host Gene: hsa-miR-576-3p
 
 
 
Disease basic information
DO ID:
1612
DO name: breast cancer
Disease details: breast cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: MCF7, MDA-MB-231, MDA-MB-468, SKBR-3, MDA-MB-453
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: SOX4
Associated microRNA: hsa-miR-576-3p
Biological function: cell proliferation, migration and invasion
Molecular mechanism: miRNA sponge
Survival: -
Supported No.:
1
Description:

hsa_circ_0012673 sponged miR-576-3p to stabilize SRY-box transcription factor 4 (SOX4), and thereby facilitating breast cancer cell proliferation, migration and invasion.

Other information
Title:

Circular RNA hsa_circ_0012673 Promotes Breast Cancer Progression via miR-576-3p/SOX4 Axis.

Journal: Mol Biotechnol
Published: 2022/7/7
PubMed ID: 35794450