circRNA basic information
circBase ID: hsa_circ_0138959
Name: -
Synonym: Circ_0138959
Host Gene: hsa-miR-495-3p
 
 
 
Disease basic information
DO ID:
 824
DO name: periodontitis
Disease details: Periodontitis
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: PDLCs
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: TRAF6
Associated microRNA: hsa-miR-495-3p
Biological function: -
Molecular mechanism: miRNA sponge
Survival: -
Supported No.:
 1
Description:

circ_0138959 upregulated the TRAF6 expression by binding to miR-495-3p, consequently aggravating LPS-induced cell damages in PDLCs.
Other information
Title:

Circ_0138959/miR-495-3p/TRAF6 axis regulates proliferation, wound healing and osteoblastic differentiation of periodontal ligament cells in periodontitis.

Journal: J Dent Sci
Published: 2022/7/6
PubMed ID: 35784154