| Detected method: |
Q
S
|
| Detected method confidence |
High
|
| Expression pattern: |
|
| Associated gene: |
GK |
| Associated microRNA: |
ssc-miR-2366 |
| Biological function: |
The overexpression of sus_circPAPPA2 significantly inhibited the differentiation of preadipocytes. The expression of sus_circPAPPA2 was increased after adding 100 nM of testosterone, and preadipocyte differentiation was significantly inhibited. |
| Molecular mechanism: |
Testosterone can affect preadipocyte differentiation by upregulating the expression of sus_circPAPPA2, sponging miR-2366 and regulating the expression of genes, such as GK. |
| Survival: |
- |
Supported
No.: |
1 |
| Description: |
This study provides basic data enhancing the understanding of the interaction between the hormone environment and mir-2366/GK to regulate trait performance in pigs. |