circRNA basic information
circBase ID: hsa_circ_0004951
Name: -
Synonym: Circ_0004951
Host Gene: -
 
 
 
Disease basic information
DO ID:
 557
DO name: kidney disease
Disease details: diabetic kidney disease
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: HK2
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: -
Biological function: -
Molecular mechanism: miRNA sponge
Survival: -
Supported No.:
 1
Description:

Circ_0004951 promotes pyroptosis of renal tubular epithelial cells in DKD via the miR-93-5p/NLRP3 inflammasome pathway, suggesting its potential for clinical diagnosis and treatment of DKD.
Other information
Title:

Circ_0004951 Promotes Pyroptosis of Renal Tubular Cells via the NLRP3 Inflammasome in Diabetic Kidney Disease.

Journal: Front Med (Lausanne)
Published: 2022/6/24
PubMed ID: 35733856