circRNA basic information
circBase ID: hsa_circ_0000705
Name: -
Synonym: Circ_0000705
Host Gene: hsa-miR-621
 
 
 
Disease basic information
DO ID:
 3748
DO name: esophagus squamous cell carcinoma
Disease details: esophageal squamous cell carcinoma
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: KYSE150, KYSE450, KYSE510, KYSE30
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: PYCR1
Associated microRNA: hsa-miR-621
Biological function: proline metabolism and malignant progression
Molecular mechanism: miRNA sponge
Survival: poor
Supported No.:
 1
Description:

circ_0000705 promoted proline metabolism and malignant progression of ESCC by regulating the miR_621/PYCR1 axis.
Other information
Title:

Circ_0000705 facilitates proline metabolism of esophageal squamous cell carcinoma cells by targeting miR-621/PYCR1 axis.

Journal: Discov Oncol
Published: 2022/6/23
PubMed ID: 35731336