circRNA basic information
circBase ID: hsa_circ_0046060
Name: hsa_circ_RPTOR
Synonym: -
Host Gene: hsa-miR-338-3p
 
 
 
Disease basic information
DO ID:
 11714
DO name: gestational diabetes
Disease details: gestational diabetes mellitus
Species: human
Species details: human
Sample type: cell line
Sample type details: L-02
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DS
Associated gene: -
Associated microRNA: hsa-miR-338-3p
Biological function: glucose metabolism and insulin resistance
Molecular mechanism: -
Survival: -
Supported No.:
 1
Description:

hsa_circ_0046060 expression in exosomes from GDM-derived UMSCs can alleviate GDM by reversing abnormal glucose metabolism and insulin resistance in vivo and in vitro.
Other information
Title:

Exosomal Circular RNA hsa_circ_0046060 of Umbilical Cord Mesenchymal Stromal Cell Ameliorates Glucose Metabolism and Insulin Resistance in Gestational Diabetes Mellitus via the miR-338-3p/G6PC2 Axis.

Journal: Int J Endocrinol
Published: 2022/6/22
PubMed ID: 35726320