circRNA basic information
circBase ID: -
Name: hsa_circ_HIPK3
Synonym: CircHIPK3
Host Gene: hsa-miR-30a-3p
 
 
 
Disease basic information
DO ID:
 8398
DO name: osteoarthritis
Disease details: osteoarthritis
Species: human
Species details: human
Sample type: tissue, PDX
Sample type details: -
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DN
Associated gene: PON2
Associated microRNA: hsa-miR-30a-3p
Biological function: chondrocyte apoptosis
Molecular mechanism: miRNA sponge
Survival: -
Supported No.:
 2
Description:

circHIPK3 regulated chondrocyte apoptosis by mitochondrial pathway, and targeting the circHIPK3/miR-30a-3p/PON2 axis.
Other information
Title:

CircHIPK3 prevents chondrocyte apoptosis and cartilage degradation by sponging miR-30a-3p and promoting PON2.

Journal: Cell Prolif
Published: 2022/6/19
PubMed ID: 35716032