circRNA basic information
circBase ID: hsa_circ_0001741
Name: hsa_circ_TNPO3
Synonym: circ_0001741
Host Gene: hsa-miR-491-5p
 
 
 
Disease basic information
DO ID:
 3748
DO name: esophagus squamous cell carcinoma
Disease details: esophageal squamous cell carcinoma
Species: human
Species details: human
Sample type: tissue
Sample type details: -
circRNA-disease information
Detected method:
Q
M
Detected method confidence High
Expression pattern:
UP
Associated gene: NOTCH3
Associated microRNA: hsa-miR-491-5p
Biological function: stemness, invasion, and migration
Molecular mechanism: miRNA sponge
Survival: poor
Supported No.:
 1
Description:

hsa_circ_0001741 promotes ESCC stemness, invasion, and migration by sponging tumor suppressor miR-491-5p to upregulate NOTCH3 expression.
Other information
Title:

hsa_circ_0001741 promotes esophageal squamous cell carcinoma stemness, invasion and migration by sponging miR-491-5p to upregulate NOTCH3 expression.

Journal: Am J Cancer Res
Published: 2022/6/14
PubMed ID: 35693080