circRNA basic information
circBase ID: hsa_circ_0006790
Name: hsa_circ_MEMO1
Synonym: Circ_0006790
Host Gene: -
 
 
 
Disease basic information
DO ID:
 3498
DO name: pancreatic ductal adenocarcinoma
Disease details: pancreatic ductal adenocarcinoma
Species: human
Species details: human
Sample type: cell line
Sample type details: PANC-1, CFPAC-1
circRNA-disease information
Detected method:
Q
M
Detected method confidence High
Expression pattern:
DS
Associated gene: -
Associated microRNA: -
Biological function: immune escape
Molecular mechanism: CBX7-catalyzed DNA hypermethylation.
Survival: -
Supported No.:
 1
Description:

MSC-derived exosomal circ_6790 could downregulate S100A11 in PDAC cells and hamper immune escape via CBX7-catalyzed DNA hypermethylation.
Other information
Title:

Circ_0006790 carried by bone marrow mesenchymal stem cell-derived exosomes regulates S100A11 DNA methylation through binding to CBX7 in pancreatic ductal adenocarcinoma.

Journal: Am J Cancer Res
Published: 2022/6/14
PubMed ID: 35693076