circRNA basic information
circBase ID: -
Name: hsa_circ_SRSF4
Synonym: CircSRSF4
Host Gene: hsa-miR-224
 
 
 
Disease basic information
DO ID:
 3347
DO name: osteosarcoma
Disease details: osteosarcoma
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: MG63, SAOS-2, U2OS, 293T
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: Rac1
Associated microRNA: hsa-miR-224
Biological function: cell proliferation and resistance to cisplatin
Molecular mechanism: miRNA sponge
Survival: -
Supported No.:
 1
Description:

circSRSF4 can be used as an miR-224 sponge to up-regulate the expression of Rac1, thereby promoting the development of osteosarcoma.
Other information
Title:

CircSRSF4 Enhances Proliferation, Invasion, and Migration to Promote the Progression of Osteosarcoma via Rac1.

Journal: Int J Mol Sci
Published: 2022/6/11
PubMed ID: 35682879