circRNA basic information
circBase ID: hsa_circ_0000064
Name: -
Synonym: Circ_0000064
Host Gene: hsa-miR-424-5p
 
 
 
Disease basic information
DO ID:
 557
DO name: kidney disease
Disease details: diabetic nephropathy
Species: human
Species details: human
Sample type: cell line
Sample type details: HRMCs
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DN
Associated gene: WNT2B
Associated microRNA: hsa-miR-424-5p
Biological function: -
Molecular mechanism: miRNA sponge
Survival: -
Supported No.:
 3
Description:

Circ_0000064 knockdown ameliorated HG-induced HRMC dysfunctions through miR-424-5p enrichment-mediated WNT2B inhibition.
Other information
Title:

Circ_0000064 knockdown attenuates high glucose-induced proliferation, inflammation and extracellular matrix deposition of mesangial cells through miR-424-5p-mediated WNT2B inhibition in cell models of diabetic nephropathy.

Journal: Clin Exp Nephrol
Published: 2022/6/10
PubMed ID: 35678923