circRNA basic information
circBase ID: hsa_circ_0003420
Name: -
Synonym: circ_0003420
Host Gene: hsa-miR-424-5p
 
 
 
Disease basic information
DO ID:
 850
DO name: lung disease
Disease details: acute lung injury
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: BEAS-2B
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: TLR4-related NF-kappaB
Associated microRNA: hsa-miR-424-5p
Biological function: -
Molecular mechanism: miRNA sponge
Survival: -
Supported No.:
 1
Description:

circ_0003420 contributed to the LPS-induced lung cell injury via activating the miR-424-5p/TLR4-related NF-kappaB signaling pathway.
Other information
Title:

Lipopolysaccharide-induced lung cell inflammation and apoptosis are enhanced by circ_0003420/miR-424-5p/TLR4 axis via inactivating the NF-kappaB signaling pathway.

Journal: Transpl Immunol
Published: 2022/6/7
PubMed ID: 35667541