circRNA basic information
circBase ID: -
Name: hsa_circ_RHOBTB3
Synonym: circRHOBTB3
Host Gene: hsa-miR-23a-3p
 
 
 
Disease basic information
DO ID:
 2394
DO name: ovarian cancer
Disease details: ovarian cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: A2780, OVCAR8, SKOV3, SKOV3-ip
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DS
Associated gene: PTEN
Associated microRNA: hsa-miR-23a-3p
Biological function: proliferation, G1/S transition, invasion, and apoptosis
Molecular mechanism: miRNA sponge
Survival: -
Supported No.:
 2
Description:

circRHOBTB3 could serve as the ceRNA of miR_23a-3p to facilitate PTEN expression, suppress proliferation, G1/S transition, invasion, and promote apoptosis in EOC.
Other information
Title:

The molecular mechanism of circRHOBTB3 inhibits the proliferation and invasion of epithelial ovarian cancer by serving as the ceRNA of miR-23a-3p.

Journal: J Ovarian Res
Published: 2022/6/2
PubMed ID: 35650643