circRNA basic information
circBase ID: -
Name: hsa_circ_PVT1
Synonym: CircPVT1
Host Gene: hsa-miR-26b-5p
 
 
 
Disease basic information
DO ID:
 3347
DO name: osteosarcoma
Disease details: osteosarcoma
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: Saos-2, MG63, U2OS, 143B
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: CCNB1
Associated microRNA: hsa-miR-26b-5p
Biological function: tumorigenesis and metastasis
Molecular mechanism: miRNA sponge
Survival: -
Supported No.:
 5
Description:

Silencing of circPVT1 notably suppressed the tumorigenesis and metastasis of OS via miR-26b-5p/CCNB1 axis.
Other information
Title:

CircPVT1 promotes the tumorigenesis and metastasis of osteosarcoma via mediation of miR-26b-5p/CCNB1 axis.

Journal: J Bone Miner Metab
Published: 2022/6/2
PubMed ID: 35648221