circRNA basic information
circBase ID: -
Name: hsa_circ_LIFR
Synonym: CircLIFR
Host Gene: hsa-miR-624-5p
 
 
 
Disease basic information
DO ID:
 684
DO name: hepatocellular carcinoma
Disease details: hepatocellular carcinoma
Species: human
Species details: human
Sample type: tissue
Sample type details: -
circRNA-disease information
Detected method:
Q
S
Detected method confidence High
Expression pattern:
DN
Associated gene: GSK-3beta
Associated microRNA: hsa-miR-624-5p
Biological function: proliferation and invasion
Molecular mechanism: miRNA sponge
Survival: poor
Supported No.:
 2
Description:

circLIFR acts as a tumor suppressor in HCC by regulating miR-624-5p and inactivating the GSK-3beta/beta-catenin signaling pathway.
Other information
Title:

CircLIFR suppresses hepatocellular carcinoma progression by sponging miR-624-5p and inactivating the GSK-3beta/beta-catenin signaling pathway.

Journal: Cell Death Dis
Published: 2022/5/18
PubMed ID: 35581180