circRNA basic information
circBase ID: hsa_circ_0000284
Name: -
Synonym: Circ_0000284
Host Gene: rno-miR-10a-5p
 
 
 
Disease basic information
DO ID:
 2913
DO name: acute pancreatitis
Disease details: acute pancreatitis
Species: rat
Species details: rat
Sample type: tissue, PDX
Sample type details: AR42J
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: DKK1
Associated microRNA: rno-miR-10a-5p
Biological function: apoptosis and inflammation
Molecular mechanism: miRNA sponge
Survival: -
Supported No.:
 1
Description:

Circ_0000284 depletion could protect caerulein-induced AR42J cells from apoptosis and inflammation by upregulating miR-10a-5p expression and activating Wnt/beta-catenin pathway.
Other information
Title:

Circ_0000284 Promoted Acute Pancreatitis Progression through the Regulation of miR-10a-5p/Wnt/beta-Catenin Pathway.

Journal: Chem Biodivers
Published: 2022/5/18
PubMed ID: 35581162