circRNA basic information
circBase ID: hsa_circ_0003423
Name: -
Synonym: Circ_0003423
Host Gene: hsa-miR-142-3p
 
 
 
Disease basic information
DO ID:
 1936
DO name: atherosclerosis
Disease details: atherosclerosis
Species: human
Species details: human
Sample type: cell line
Sample type details: HUVECs
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DN
Associated gene: SIRT3
Associated microRNA: hsa-miR-142-3p
Biological function: proliferation, migration, and angiogenesis
Molecular mechanism: miRNA sponge
Survival: -
Supported No.:
 1
Description:

Circ_0,003,423 protected HUVECs from ox-LDL-induced dysfunction by sponging miR-142-3p and activating SIRT3/SOD2 signaling.
Other information
Title:

Circ_0003423 Alleviates Oxidized Low-Density Lipoprotein-Induced Endothelial Cell Injury by Sponging miR-142-3p and Activating Sirtuin 3/Superoxide Dismutase 2 Pathway.

Journal: J Surg Res
Published: 2022/5/18
PubMed ID: 35580464