circRNA basic information
circBase ID: -
Name: hsa_circ_HIPK3
Synonym: -
Host Gene: hsa-miR-124-3p, hsa-miR-148b-3p
 
 
 
Disease basic information
DO ID:
 557
DO name: kidney disease
Disease details: septic acute kidney injury
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: HK-2
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: KLF6; DNMT1/3a
Associated microRNA: hsa-miR-124-3p, hsa-miR-148b-3p
Biological function: inflammatory responses; cell senescence
Molecular mechanism: miRNA sponge
Survival: -
Supported No.:
 3
Description:

circHIPK3 aggravated SAKI inflammatory responses via miR-124-3p/KLF6 and accelerated SAKI cell senescence via miR-148b-3p/DNMT1/3a.
Other information
Title:

Mechanism of circHIPK3-miRNA-124-3p/miRNA-148b-3p-Mediated Inflammatory Responses and Cell Senescence in Candida albicans-Induced Septic Acute Kidney Injury.

Journal: Gerontology
Published: 2022/5/17
PubMed ID: 35576907